The affective computing group at MIT is doing very interesting stuff for autistic people: http://affect.media.mit.edu/projects.php?id=2294

People who have difficulty communicating verbally (such as many people with autism) sometimes send nonverbal messages that do not match what is happening inside them. For example, a child might look calm and receptive to learning, while having a heart rate of over 120 bpm and being on the verge of a meltdown or shutdown. This mismatch can lead to serious problems, including misunderstandings such as "he became aggressive for no reason." We are creating new technologies to address this fundamental communication problem and enable the first long-term, ultra-dense longitudinal data analysis of emotion-related physiological signals. We hope to equip individuals with personalized tools to understand the regulatory influences of emotion on their own state (e.g., "what state helps me best maintain my attention and focus for learning?"), and also enable scientists to accurately measure and understand the role of emotion regulation in autism.